Location: Mountain View, CA
Position Type: Full-Time
Position Summary
AbTherx is a biotechnology company advancing the next generation of antibody therapeutics. By leveraging its proprietary Atlas™ Mice transgenic technologies, the company enables the rapid identification of highly diverse, high‑quality, and developable therapeutic candidates for the industry’s most challenging drug targets. Built on the deep experience of an industry‑leading scientific team, the AbTherx platform empowers drug developers to reliably deliver innovative medicines to unlock difficult targets with speed and efficiency.
We are seeking a highly motivated individual to join our Antibody Discovery team as a Senior Research Associate. The successful candidate will contribute to our efforts for the discovery of monoclonal antibodies using hybridoma and single B cell technologies from AbTherx’s Atlas™ Mice. This role requires operating with minimal supervision to deliver on projects against a variety of targets.
Key Responsibilities
- Execute antibody discovery campaigns to generate monoclonal antibodies using hybridoma and/or B-cell technology platforms
- Evaluate serum titres, process lymphoid mouse tissues, and perform electro-fusions and subcloning
- Screen and characterize antibodies for binding and functional activity using ELISA, flow cytometry, biochemical and cell-based assays
- Maintain, expand, cryopreserve, and clone cell lines
- Explore new technologies, opportunities, and automation to improve/streamline the antibody discovery workflows and processes
- Maintain accurate registering of experimental results and sample tracking, and provide regular progress updates
Qualification Requirements
- MS in Molecular Biology, Biochemistry, Immunology or related field with 2+ years of industry experience, or BS with 5+ years of industry experience with strong success track record
- Hands-on experience with antibody discovery using hybridoma technology and/or single B cell approach is a must
- Small animal handling techniques are beneficial but not required
- Hands-on experience with cell biology including mammalian cell culture, transfection, and running functional cell-based assays
- Hands-on experience with protein-protein interaction using a variety of methods such as quantitative ELISA and flow cytometry
- Experience with automation and high-throughput assay development is strongly preferred
- Experience with molecular biology techniques is desirable
- Ability to work independently and as part of a team in a startup environment
- Highly organized and energetic person with excellent attention to details, time management, and communication skills
Why Join AbTherx?
At AbTherx, we’re driven to create new medicines that improve human health. We are passionate about our technologies’ ability to positively impact the future of medicine and recognize the vital role our team plays in shaping our science and culture.
We support our employees by providing a competitive total compensation package, including stock options, an annual performance bonus incentive program, a comprehensive benefits package, paid time off, two one-week company shutdowns each year in the summer and winter, and opportunities for professional development. We regularly hold company-wide meetings to foster open communication and a supportive community.
Join us in our dynamic startup environment where you’ll partner with colleagues of diverse backgrounds and abilities, people who contribute to all aspects of what makes our platform powerful—from technology development to drug discovery to business operations, and so much more.
AbTherx is an Equal Opportunity Employer and committed to creating an inclusive environment for all employees. We do not discriminate on the basis of race, color, religion, age, sex, creed, national origin, ancestry, citizenship status, marital or domestic or civil union status, familial status, affectional or sexual orientation, gender identity or expression, genetics, disability, military eligibility or veteran status, or any other protected status.
Apply for this job by emailing your resume to info@abtherx.com.
