Atlas™ Mouse Platform
AbTherx’s Atlas Mice are engineered to create high-quality human antibodies to access all types of targets, from simple to complex, including GPCRs and ion channels. These transgenic technologies are licensed as part of an exclusive partnership with Gilead.
Target GPCRs and Ion Channels with Long CDR3 Mouse
- Unlocks access to buried epitopes within GPCRs, ion channels, and other difficult targets
- Fully human antibodies that minimize developability and immunogenicity risks
- Leverages a rare but naturally occurring human mechanism to generate long CDR3 regions
Better Bispecific Antibodies with Binary Fixed Light Chain Mouse
- Enables native-like IgG bispecifics that improve manufacturability and developability
- Increases hit rate and expands antibody repertoire by including two fixed light chain options, with optimized heavy-light chain pairing
- Novel, patent-pending design overcomes the limitations of current technologies
Updated Industry Standard with Full Human Diversity Mouse
- Generates fully human antibodies with affinities into the single-digit picomolar range
- Thoughtfully designed to capture the full human heavy and kappa light chain repertoire
- Designed to minimize immunogenicity and developability risks by excluding rare V genes
